SERPREDICT: DETECTION OF TISSUE- OR TUMOR-SPECIFIC ISOFORMS GENERATED THROUGH EXONIZATION OF TRANSPOSABLE ELEMENTS

SERpredict: Detection of tissue- or tumor-specific isoforms generated through exonization of transposable elements

Abstract Background Transposed elements (TEs) are known to affect transcriptomes, because either new exons are generated from intronic transposed elements (this is called exonization), or the element inserts into the exon, leading to a new transcript.Several examples in the literature show that isoforms generated by an exonization are specific to a

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Stochastic heat engines beyond a unique definition of temperature

When Carnot and Stirling initially conceptualized heat engines, temperature unambiguously represented our everyday perception of cold and hot.However, as this energy scale is expanded to measure the strength of noise in general nonequilibrium heat baths, such as those consisting of bacteria or DRY HAIR SHAMPOO active particles, it takes on differen

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